Adults :Take 5-50 drops daily or as directed by your health care practitioner. Sensitivity to melatonin varies from person to person. Take once a day, at or before bedtime. Do not drive or operate machinery for 5 hours after taking melatonin.For jet lag :Take once a day at bedtime, after dark, at destination, until adaptation to the new day/night cycle for occasional short-term use.For sleep restriction/altered sleep schedule; for sleep phase delay syndrome; or to restore the sleep-wake cycle:Consult a health care practitioner for use beyond 4 weeks.